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Evidence-based use of FFP: the influence of a priming strategy without FFP during CPB on postoperative coagulation and recovery in pediatric patients.

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Author(s): Miao, X; Liu, J; Zhao, M; Cui, Y; Feng, Z; Zhao, J; Long, C; Li, S; Yan, F; Wang, X; Hu, S
Source:
Perfusion. Mar2015, Vol. 30 Issue 2, p140-147. 8p.

Additional Information
- Subject Terms:
  CARDIOPULMONARY bypass; CONGENITAL heart disease; ACADEMIC medical centers; ALGORITHMS; BLOOD coagulation; BLOOD plasma; CHI-squared test; HEMORRHAGE prevention; STRATEGIC planning; T-test (Statistics); THROMBELASTOGRAPHY; RANDOMIZED controlled trials; TREATMENT effectiveness; DATA analysis software; DESCRIPTIVE statistics; MANN Whitney U Test; CHILDREN; SURGERY
- Subject Terms:
  CHINA
- Abstract:
  The article discusses the study on the effects of a priming strategy without fresh frozen plasma (FPP) during cardiopulmonary bypass (CPB) on the coagulation after surgery and clinical recovery in pediatric patients, that found no clinical benefits to prophylactic use of FFP in priming solution. Findings discussed include safe and effective use of artificial colloids as FFP substitute in pump prime, and effectivity of thromboelastography (TEG) to assess postoperative coagulation function.

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