Effect of intermittent normobaric hyperoxia for treatment of neuropathic pain in Chinese patients with spinal cord injury

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  • Source:
    Spinal cord 2015 53 3, 238 (238-242) Published by: Nature Publishing Group United Kingdom
  • Additional Information
    • Author(s):
      Gui Y, Li H, Zhao M, Yang Q, Kuang X
    • Contact Information:
      Department of Anesthesiology, First Affiliated Hospital, Nanhua University, China
    • Language:
      English
    • Publication Type:
      Journal: Article
    • Record Status:
      This record is updated this issue.
    • Abstract:
      Study design: Prospective, randomized and controlled study. Objectives: The aim of the study was to investigate the effect of intermittent normobaric hyperoxia (InHO) for treatment of neuropathic pain in patients with spinal cord injury (SCI). Setting: The First Affiliated Hospital of Nanhua University, Hengyang, Hunan Province, China. Methods: Patients with SCI from Hunan Province were recruited from the First Affiliated Hospital of Nanhua University. History, duration, localization and characteristics of pain were recorded. Visual analog scale (VAS), the Patient Global Impression of Change (PGIC) and Short Form-36 walk-wheel (SF-36ww) was used to investigate the effect of InHO. Patients were randomly assigned to study and control groups. In study group, patients were exposed to pure oxygen via non-rebreathing reservoir mask, which increased the provided oxygen at a rate of 7 l min -1 for 1 or 4 h daily in 2 weeks. While in control group, patients breathed air via non-rebreathing reservoir mask at the same rate. Results: A total of 62 SCI patients with neuropathic pain were included in the study. The mean age of the patients was 36.85±10.71 years. Out of 62 patients, 21 were tetraplegic and 41 were paraplegic. Overall, 14 patients had complete SCI while 48 patients had incomplete injuries. Three groups were similar with respect to age, gender, duration, smoker or not, level and severity of injury. In the 4 h per day InHO groups, a statistically significant reduction of the VAS values was observed (P
    • EMBASE keywords:
      adult; analgesia; article; controlled study; disease duration; double blind procedure; female; human; *hyperoxia; injury severity; *intermittent normobaric hyperoxia; major clinical study; male; *neuropathic pain /disease management; paraplegia; priority journal; prospective study; quadriplegia; quality of life; randomized controlled trial; reservoir; Short Form 36; *spinal cord injury; visual analog scale
    • Accession Number:
      600219942
    • Source:
      This document should be cited as: Gui Y Li H Zhao M Yang Q Kuang X. Effect of intermittent normobaric hyperoxia for treatment of neuropathic pain in Chinese patients with spinal cord injury 2015 (The Cochrane Controlled Trials Register (CCTR/CENTRAL). DOI: 10.1038/sc.2014.161. Oxford: Update Software. Updated quarterly.
    • Accession Number:
      CN-01209479
  • Citations
    • ABNT:
      GUI Y et al. Effect of intermittent normobaric hyperoxia for treatment of neuropathic pain in Chinese patients with spinal cord injury. Spinal cord, [s. l.], v. 53, n. 3, p. 238–242, 2015. DOI 10.1038/sc.2014.161. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=cgh&AN=CN-01209479. Acesso em: 14 abr. 2021.
    • AMA 11th Edition:
      Gui Y, Li H, Zhao M, Yang Q, Kuang X. Effect of intermittent normobaric hyperoxia for treatment of neuropathic pain in Chinese patients with spinal cord injury. Spinal cord. 2015;53(3):238-242. doi:10.1038/sc.2014.161
    • APA 7th Edition:
      Gui Y, Li H, Zhao M, Yang Q, & Kuang X. (2015). Effect of intermittent normobaric hyperoxia for treatment of neuropathic pain in Chinese patients with spinal cord injury. Spinal Cord, 53(3), 238–242. https://doi.org/10.1038/sc.2014.161
    • Chicago 17th Edition:
      Gui Y, Li H, Zhao M, Yang Q, and Kuang X. 2015. “Effect of Intermittent Normobaric Hyperoxia for Treatment of Neuropathic Pain in Chinese Patients with Spinal Cord Injury.” Spinal Cord 53 (3): 238–42. doi:10.1038/sc.2014.161.
    • Harvard:
      Gui Y et al. (2015) ‘Effect of intermittent normobaric hyperoxia for treatment of neuropathic pain in Chinese patients with spinal cord injury’, Spinal cord, 53(3), pp. 238–242. doi: 10.1038/sc.2014.161.
    • Harvard: Australian:
      Gui Y, Li H, Zhao M, Yang Q & Kuang X 2015, ‘Effect of intermittent normobaric hyperoxia for treatment of neuropathic pain in Chinese patients with spinal cord injury’, Spinal cord, vol. 53, no. 3, pp. 238–242, viewed 14 April 2021, .
    • MLA 8th Edition:
      Gui Y, et al. “Effect of Intermittent Normobaric Hyperoxia for Treatment of Neuropathic Pain in Chinese Patients with Spinal Cord Injury.” Spinal Cord, vol. 53, no. 3, Jan. 2015, pp. 238–242. EBSCOhost, doi:10.1038/sc.2014.161.
    • Chicago 17th Edition:
      Gui Y, Li H, Zhao M, Yang Q, and Kuang X. “Effect of Intermittent Normobaric Hyperoxia for Treatment of Neuropathic Pain in Chinese Patients with Spinal Cord Injury.” Spinal Cord 53, no. 3 (January 1, 2015): 238–42. doi:10.1038/sc.2014.161.
    • Vancouver/ICMJE:
      Gui Y, Li H, Zhao M, Yang Q, Kuang X. Effect of intermittent normobaric hyperoxia for treatment of neuropathic pain in Chinese patients with spinal cord injury. Spinal cord [Internet]. 2015 Jan 1 [cited 2021 Apr 14];53(3):238–42. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=cgh&AN=CN-01209479