Microsystems, smart textiles, telemedicine, smart implants and sensor-controlled medical devices have become important enablers for monitoring and treatment in both inpatient and outpatient care. Indeed, micro and nano technologies have tremendous potential for increasing access to care whilst managing healthcare costs. They are set to be at the heart of evolutionary and revolutionary changes in healthcare, and are crucial, not only for the future of medicine, but also for the improvement of health care and welfare processes today and tomorrow. This book presents the proceedings of the 2012 pHealth conference, held in Porto, Portugal, in June 2012. The pHealth conference has emerged as the leading international meeting on wearable micro and nano technologies for personalized medicine, attracting scientists from various disciplines, clinicians, as well as policy makers from the healthcare industry, hospital administration and allied professionals. The book includes keynotes, invited speeches and selected submitted contributions. The areas covered include: the pHealth approach, new approaches to diagnosis and therapy, monitoring special diseases, system architecture, design and implementation, wearable sensor systems, smartphone applications and ambient assisted living. Over the years, pHealth has given visibility to the tremendous potential of micro and nano technologies, not only for the future of medicine, but also for the improvement of healthcare processes today. This book will be of interest to all those involved with the provision of health and welfare services, and also to companies engaged in the development of micro and nano technologies.