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Smoking cessation during alcohol treatment: a randomized trial of combination nicotine patch plus nicotine gum.

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  • Additional Information
    • Publication Year:
      2009
    • Author-Supplied Keywords:
      Alcoholism
      clinical trial
      combination
      nicotine
      nicotine polacrilex
      smoking
      smoking cessation
      tobacco
      transdermal
    • NAICS/Industry Codes:
      NAICS/Industry Codes 622210 Psychiatric and Substance Abuse Hospitals
      623220 Residential Mental Health and Substance Abuse Facilities
      541712 Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
      325411 Medicinal and Botanical Manufacturing
      621999 All Other Miscellaneous Ambulatory Health Care Services
      621990 All other ambulatory health care services
    • Abstract:
      Aims The primary aim was to compare the efficacy of smoking cessation treatment using a combination of active nicotine patch plus active nicotine gum versus therapy consisting of active nicotine patch plus placebo gum in a sample of alcohol-dependent tobacco smokers in an early phase of out-patient alcohol treatment. A secondary aim was to determine whether or not there were any carry-over effects of combination nicotine replacement on drinking outcomes. Design Small-scale randomized double-blind placebo-controlled clinical trial with 1-year smoking and drinking outcome assessment. Setting Two out-patient substance abuse clinics provided a treatment platform of behavioral alcohol and smoking treatment delivered in 3 months of weekly sessions followed by three monthly booster sessions. Participants Participants were 96 men and women with a diagnosis of alcohol abuse or dependence and smoking 15 or more cigarettes per day. Intervention All participants received open-label transdermal nicotine patches and were randomized to receive either 2 mg nicotine gum or placebo gum under double-blind conditions. Findings Analysis of 1-year follow-up data revealed that patients receiving nicotine patch plus active gum had better smoking outcomes than those receiving patch plus placebo gum on measures of time to smoking relapse and prolonged abstinence at 12 months. Alcohol outcomes were not significantly different across medication conditions. Conclusions Results of this study were consistent with results of larger trials of smokers without alcohol problems, showing that combination therapy (nicotine patch plus gum) is more effective than monotherapy (nicotine patch) for smoking cessation. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Copyright of Addiction is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
    • ISSN:
      09652140
    • Accession Number:
      43522492
  • Citations
    • ABNT:
      COONEY, N. L. et al. Smoking cessation during alcohol treatment: a randomized trial of combination nicotine patch plus nicotine gum. Addiction, [s. l.], v. 104, n. 9, p. 1588, 2009. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=43522492. Acesso em: 4 dez. 2020.
    • AMA:
      Cooney NL, Cooney JL, Perry BL, et al. Smoking cessation during alcohol treatment: a randomized trial of combination nicotine patch plus nicotine gum. Addiction. 2009;104(9):1588. Accessed December 4, 2020. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=43522492
    • APA:
      Cooney, N. L., Cooney, J. L., Perry, B. L., Carbone, M., Cohen, E. H., Steinberg, H. R., Pilkey, D. T., Sevarino, K., Oncken, C. A., & Litt, M. D. (2009). Smoking cessation during alcohol treatment: a randomized trial of combination nicotine patch plus nicotine gum. Addiction, 104(9), 1588.
    • Chicago/Turabian: Author-Date:
      Cooney, Ned L., Judith L. Cooney, Bridget L. Perry, Michael Carbone, Emily H. Cohen, Howard R. Steinberg, David T. Pilkey, Kevin Sevarino, Cheryl A. Oncken, and Mark D. Litt. 2009. “Smoking Cessation during Alcohol Treatment: A Randomized Trial of Combination Nicotine Patch plus Nicotine Gum.” Addiction 104 (9): 1588. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=43522492.
    • Harvard:
      Cooney, N. L. et al. (2009) ‘Smoking cessation during alcohol treatment: a randomized trial of combination nicotine patch plus nicotine gum’, Addiction, 104(9), p. 1588. Available at: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=43522492 (Accessed: 4 December 2020).
    • Harvard: Australian:
      Cooney, NL, Cooney, JL, Perry, BL, Carbone, M, Cohen, EH, Steinberg, HR, Pilkey, DT, Sevarino, K, Oncken, CA & Litt, MD 2009, ‘Smoking cessation during alcohol treatment: a randomized trial of combination nicotine patch plus nicotine gum’, Addiction, vol. 104, no. 9, p. 1588, viewed 4 December 2020, .
    • MLA:
      Cooney, Ned L., et al. “Smoking Cessation during Alcohol Treatment: A Randomized Trial of Combination Nicotine Patch plus Nicotine Gum.” Addiction, vol. 104, no. 9, Sept. 2009, p. 1588. EBSCOhost, search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=43522492.
    • Chicago/Turabian: Humanities:
      Cooney, Ned L., Judith L. Cooney, Bridget L. Perry, Michael Carbone, Emily H. Cohen, Howard R. Steinberg, David T. Pilkey, Kevin Sevarino, Cheryl A. Oncken, and Mark D. Litt. “Smoking Cessation during Alcohol Treatment: A Randomized Trial of Combination Nicotine Patch plus Nicotine Gum.” Addiction 104, no. 9 (September 2009): 1588. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=43522492.
    • Vancouver/ICMJE:
      Cooney NL, Cooney JL, Perry BL, Carbone M, Cohen EH, Steinberg HR, et al. Smoking cessation during alcohol treatment: a randomized trial of combination nicotine patch plus nicotine gum. Addiction [Internet]. 2009 Sep [cited 2020 Dec 4];104(9):1588. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=43522492