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Differences between responders and nonresponders to cocaine cues in the laboratory

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  • Additional Information
    • Affiliation:
      Yale University School of Medicine USA
    • Note:
      This research was supported by NIDA grants P50-DA04060, R18-DA06190, K02-DA0112 (TRK).
    • Abstract:
      Previous research has shown that a majority of drug-dependent subjects respond to drug cues in the laboratory with increased craving; however, approximately one-third are not cue responsive. The current study examined differences between responders and nonresponders to cocaine cues in a sample of 69 cocaine-dependent methadone patients. Subjects completed questionnaires assessing selected dimensions of addiction and participated in a cue-reactivity protocol that assessed both cocaine craving and cocaine aversion in response to cues. Four groups of subjects were identified on the basis of their cue responses: (a)increased craving plus decreased aversion; (b)increasing craving only; (c) decreased aversion only; (d) no increase in craving and no decrease in aversion (“nonresponders”). No group differences were found in severity of cocaine dependence, depression, or on any demographic variable, with the exception of parental status. Group differences were found on measures of cocaine expectancies and self-efficacy. There is a discussion of the bearing of these findings upon explanations offered in the literature for nonreactivity to drug cues.
    • ISSN:
      0306-4603
    • Accession Number:
      10.1016/0306-4603(94)00066-2
    • Accession Number:
      0306460394000662
    • Copyright:
      Copyright @ unknown. Published by Elsevier Ltd
  • Citations
    • ABNT:
      AVANTS, S. K. et al. Differences between responders and nonresponders to cocaine cues in the laboratory. Addictive Behaviors, [s. l.], v. 20, n. 2, p. 215–224, 1995. DOI 10.1016/0306-4603(94)00066-2. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edselp&AN=0306460394000662. Acesso em: 21 set. 2020.
    • AMA:
      Avants SK, Margolin A, Kosten TR, Cooney NL. Differences between responders and nonresponders to cocaine cues in the laboratory. Addictive Behaviors. 1995;20(2):215-224. doi:10.1016/0306-4603(94)00066-2
    • APA:
      Avants, S. K., Margolin, A., Kosten, T. R., & Cooney, N. L. (1995). Differences between responders and nonresponders to cocaine cues in the laboratory. Addictive Behaviors, 20(2), 215–224. https://doi.org/10.1016/0306-4603(94)00066-2
    • Chicago/Turabian: Author-Date:
      Avants, S.Kelly, Arthur Margolin, Thomas R. Kosten, and Ned L. Cooney. 1995. “Differences between Responders and Nonresponders to Cocaine Cues in the Laboratory.” Addictive Behaviors 20 (2): 215–24. doi:10.1016/0306-4603(94)00066-2.
    • Harvard:
      Avants, S. K. et al. (1995) ‘Differences between responders and nonresponders to cocaine cues in the laboratory’, Addictive Behaviors, 20(2), pp. 215–224. doi: 10.1016/0306-4603(94)00066-2.
    • Harvard: Australian:
      Avants, SK, Margolin, A, Kosten, TR & Cooney, NL 1995, ‘Differences between responders and nonresponders to cocaine cues in the laboratory’, Addictive Behaviors, vol. 20, no. 2, pp. 215–224, viewed 21 September 2020, .
    • MLA:
      Avants, S.Kell., et al. “Differences between Responders and Nonresponders to Cocaine Cues in the Laboratory.” Addictive Behaviors, vol. 20, no. 2, Jan. 1995, pp. 215–224. EBSCOhost, doi:10.1016/0306-4603(94)00066-2.
    • Chicago/Turabian: Humanities:
      Avants, S.Kelly, Arthur Margolin, Thomas R. Kosten, and Ned L. Cooney. “Differences between Responders and Nonresponders to Cocaine Cues in the Laboratory.” Addictive Behaviors 20, no. 2 (January 1, 1995): 215–24. doi:10.1016/0306-4603(94)00066-2.
    • Vancouver/ICMJE:
      Avants SK, Margolin A, Kosten TR, Cooney NL. Differences between responders and nonresponders to cocaine cues in the laboratory. Addictive Behaviors [Internet]. 1995 Jan 1 [cited 2020 Sep 21];20(2):215–24. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edselp&AN=0306460394000662