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Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy

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  • Additional Information
    • Affiliation:
      a Department of Rasashastra and Bhaishajya Kalpana Including Drug Research, I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar, Gujarat, India
      b Department of Basic Principles including Drug Research, I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar, Gujarat, India
    • Note:
      Foundation Project: Supported by Institute of Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.
    • Keywords:
      Diabetes mellitus
      Guduchi, Herbal remedies
      Tinospora cordifolia, Traditional medicine
    • Abstract:
      Currently, available conventional options for diabetes mellitus have certain limitations of their own, and options from medicinal plants with antihyperglycemic activities are being searched to meet the need. Antidiabetic properties of Tinospora cordifolia are highly appreciated in Ayurveda and even in recent modern researches. Several studies on its extracts (viz. immune- modulatory, anti-hyperglycemic, antioxidant, adaptogenic, hepatoprotective, hormone regulator etc.) and isolated phytoconstituents (like tinosporin, berberine, jatrorrhizine etc.) have reported that it is a preventive and curative antidiabetic herb, which are substantiated by clinical trials. Scattered information pertaining to antidiabetic potential of Tinospora is reported. Present review encompasses (i) in-depth information of reported antidiabetic activities of the plant in light of available experimental and clinical studies, and (ii) understanding on the possible mechanism of its action in combating the complex pathology of diabetes.
    • ISSN:
      2221-1691
    • Accession Number:
      10.1016/j.apjtb.2014.12.007
    • Accession Number:
      S2221169114000094
    • Copyright:
      Copyright © 2015 Hainan Medical University Published by Elsevier B.V. All rights reserved.
  • Citations
    • ABNT:
      SHARMA, R. et al. Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy. Asian Pacific Journal of Tropical Biomedicine, [s. l.], 2014. DOI 10.1016/j.apjtb.2014.12.007. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edselp&AN=S2221169114000094. Acesso em: 22 out. 2020.
    • AMA:
      Sharma R, Amin H, Galib, Prajapati PK. Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy. Asian Pacific Journal of Tropical Biomedicine. January 2014. doi:10.1016/j.apjtb.2014.12.007
    • APA:
      Sharma, R., Amin, H., Galib, & Prajapati, P. K. (2014). Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy. Asian Pacific Journal of Tropical Biomedicine. https://doi.org/10.1016/j.apjtb.2014.12.007
    • Chicago/Turabian: Author-Date:
      Sharma, Rohit, Hetal Amin, Galib, and Pradeep Kumar Prajapati. 2014. “Antidiabetic Claims of Tinospora Cordifolia (Willd.) Miers: Critical Appraisal and Role in Therapy.” Asian Pacific Journal of Tropical Biomedicine, January. doi:10.1016/j.apjtb.2014.12.007.
    • Harvard:
      Sharma, R. et al. (2014) ‘Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy’, Asian Pacific Journal of Tropical Biomedicine. doi: 10.1016/j.apjtb.2014.12.007.
    • Harvard: Australian:
      Sharma, R, Amin, H, Galib & Prajapati, PK 2014, ‘Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy’, Asian Pacific Journal of Tropical Biomedicine, viewed 22 October 2020, .
    • MLA:
      Sharma, Rohit, et al. “Antidiabetic Claims of Tinospora Cordifolia (Willd.) Miers: Critical Appraisal and Role in Therapy.” Asian Pacific Journal of Tropical Biomedicine, Jan. 2014. EBSCOhost, doi:10.1016/j.apjtb.2014.12.007.
    • Chicago/Turabian: Humanities:
      Sharma, Rohit, Hetal Amin, Galib, and Pradeep Kumar Prajapati. “Antidiabetic Claims of Tinospora Cordifolia (Willd.) Miers: Critical Appraisal and Role in Therapy.” Asian Pacific Journal of Tropical Biomedicine, January 1, 2014. doi:10.1016/j.apjtb.2014.12.007.
    • Vancouver/ICMJE:
      Sharma R, Amin H, Galib, Prajapati PK. Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy. Asian Pacific Journal of Tropical Biomedicine [Internet]. 2014 Jan 1 [cited 2020 Oct 22]; Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edselp&AN=S2221169114000094