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Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy

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  • Additional Information
    • Affiliation:
      a Department of Rasashastra and Bhaishajya Kalpana Including Drug Research, I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar, Gujarat, India
      b Department of Basic Principles including Drug Research, I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar, Gujarat, India
    • Note:
      PEER REVIEW
      Peer reviewer
      Dr. Arun Kumar, Associate Professor, Department of Biochemistry, Manipal College of Medical Sciences, Phulbari Campus, Pokhara, Nepal.
      Tel: +977-9816664537
      E-mail: [email protected]
      Comments
      Over all, the paper is informative. This is worth to be published as the readers would be benefitted and learn the properties of T. cordifolia which is widely used as anti-diabetic medicine.
      Details on Page 74
      Foundation Project: Supported by Institute of Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.
      Available online 5 Oct 2014
    • Keywords:
      Diabetes mellitus
      Guduchi
      Herbal remedies
      Tinospora cordifolia
      Traditional medicine
    • Subject Terms:
    • Abstract:
      Currently, available conventional options for diabetes mellitus have certain limitations of their own, and options from medicinal plants with antihyperglycemic activities are being searched to meet the need. Antidiabetic properties of Tinospora cordifolia are highly appreciated in Ayurveda and even in recent modern researches. Several studies on its extracts (viz. immune- modulatory, anti-hyperglycemic, antioxidant, adaptogenic, hepatoprotective, hormone regulator etc.) and isolated phytoconstituents (like tinosporin, berberine, jatrorrhizine etc.) have reported that it is a preventive and curative antidiabetic herb, which are substantiated by clinical trials. Scattered information pertaining to antidiabetic potential of Tinospora is reported. Present review encompasses (i) in-depth information of reported antidiabetic activities of the plant in light of available experimental and clinical studies, and (ii) understanding on the possible mechanism of its action in combating the complex pathology of diabetes.
    • ISSN:
      2221-1691
    • Accession Number:
      10.1016/S2221-1691(15)30173-8
    • Accession Number:
      S2221169115301738
    • Copyright:
      Copyright © null
  • Citations
    • ABNT:
      SHARMA, R. et al. Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy. Asian Pacific Journal of Tropical Biomedicine, [s. l.], v. 5, n. 1, p. 68–78, 2015. DOI 10.1016/S2221-1691(15)30173-8. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edselp&AN=S2221169115301738. Acesso em: 24 out. 2020.
    • AMA:
      Sharma R, Amin H, Galib, Prajapati PK. Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy. Asian Pacific Journal of Tropical Biomedicine. 2015;5(1):68-78. doi:10.1016/S2221-1691(15)30173-8
    • APA:
      Sharma, R., Amin, H., Galib, & Prajapati, P. K. (2015). Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy. Asian Pacific Journal of Tropical Biomedicine, 5(1), 68–78. https://doi.org/10.1016/S2221-1691(15)30173-8
    • Chicago/Turabian: Author-Date:
      Sharma, Rohit, Hetal Amin, Galib, and Pradeep Kumar Prajapati. 2015. “Antidiabetic Claims of Tinospora Cordifolia (Willd.) Miers: Critical Appraisal and Role in Therapy.” Asian Pacific Journal of Tropical Biomedicine 5 (1): 68–78. doi:10.1016/S2221-1691(15)30173-8.
    • Harvard:
      Sharma, R. et al. (2015) ‘Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy’, Asian Pacific Journal of Tropical Biomedicine, 5(1), pp. 68–78. doi: 10.1016/S2221-1691(15)30173-8.
    • Harvard: Australian:
      Sharma, R, Amin, H, Galib & Prajapati, PK 2015, ‘Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy’, Asian Pacific Journal of Tropical Biomedicine, vol. 5, no. 1, pp. 68–78, viewed 24 October 2020, .
    • MLA:
      Sharma, Rohit, et al. “Antidiabetic Claims of Tinospora Cordifolia (Willd.) Miers: Critical Appraisal and Role in Therapy.” Asian Pacific Journal of Tropical Biomedicine, vol. 5, no. 1, Jan. 2015, pp. 68–78. EBSCOhost, doi:10.1016/S2221-1691(15)30173-8.
    • Chicago/Turabian: Humanities:
      Sharma, Rohit, Hetal Amin, Galib, and Pradeep Kumar Prajapati. “Antidiabetic Claims of Tinospora Cordifolia (Willd.) Miers: Critical Appraisal and Role in Therapy.” Asian Pacific Journal of Tropical Biomedicine 5, no. 1 (January 1, 2015): 68–78. doi:10.1016/S2221-1691(15)30173-8.
    • Vancouver/ICMJE:
      Sharma R, Amin H, Galib, Prajapati PK. Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy. Asian Pacific Journal of Tropical Biomedicine [Internet]. 2015 Jan 1 [cited 2020 Oct 24];5(1):68–78. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edselp&AN=S2221169115301738