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Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren.

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  • Additional Information
    • Author(s):
    • Address:
      Wageningen University, Wageningen, Netherlands.
    • Publication Information:
      Netherlands
    • Abstract:
      This thesis aims to provide proof of principle whether biofortified yellow cassava can improve the vitamin A status of schoolchildren in Kenya. The research was conducted in Kibwezi district, Eastern Kenya, during May-November 2012. First the effect of daily consumption of yellow cassava was assessed in 342 primary school children in a randomized controlled feeding trial with serum retinol concentration as primary outcome. Furthermore, the sensory and cultural acceptability of yellow cassava were investigated in a cross-sectional study (n=140) in 3 primary schools for children as well as their caretakers. Next, the diagnostic performance of several proxy markers to assess vitamin A deficiency was studied in comparison with serum retinol concentration as a field based method to assess vitamin A deficiency (n=375). And last, the dietary intake data of children in the randomized controlled trial were used to model the potential contribution of yellow cassava to the nutrient adequacy of micronutrient intake using linear programming. The randomized controlled feeding trial collected complete data for 337 children with a compliance of 100%. Primary analyses (per protocol) showed that serum retinol concentrations in the yellow cassava group increased with 0.04 µmol/litre (95% CI: 0.00-0.07 µmol/litre) compared to the white cassava group and secondary analyses showed that serum β-carotene concentration increased with 524% (448-608%). No evidence of effect modification by initial vitamin A status, zinc status or polymorphisms in the β-carotene monooxygenase gene was found. In the acceptability study, 72% of caretakers and children were able to detect a significant difference in taste between white and yellow cassava and indicated to prefer yellow cassava because of its soft texture, sweet taste and attractive colour. Serum concentrations of retinol binding protein, transthyretin and C-reactive protein combined showed excellent diagnostic performance in estimating vitamin A deficiency in primary school children, with an area under the curve of 0.98. Adding yellow cassava to the diet as a school lunch improved the nutrient adequacy of the diet of schoolchildren; however, even with the addition of nutrient dense foods such as fish and oil, the nutrient adequacy could not be ensured for fat, riboflavin, niacin, folate and vitamin A. In conclusion, consumption of yellow cassava is acceptable and improves the serum retinol concentrations of primary school children in Kenya. The combination of 3 proxy markers is a promising approach to measure vitamin A deficiency in a low resource setting. Yellow cassava contributes to a better nutrient adequacy but should be accompanied by additional dietary guidelines and interventions to fill the remaining nutrient gaps.
    • Number of References:
      many ref.
    • Subject Terms:
      Tropical Diseases;Human Nutrition;Postharvest Research;Horticultural Science
    • Subject Terms:
    • Accession Number:
      axerophthol, carrier proteins, child care workers, color, diet preferences, folacin, folate, fortified food, hypovitaminosis A, manioc, niacin, nutritional status, organoleptic properties, retinol-binding proteins, school kids, schoolchildren, source fat, tapioca plant, taste preferences, vitamin A, vitamin A alcohol, vitamin A1, vitamin B2
    • CABICODES:
      Crop Produce (QQ050)
      Food Composition and Quality (QQ500)
      Human Nutrition (General) (VV100)
      Diet Studies (VV110)
      Physiology of Human Nutrition (VV120)
      Nutrition Related Disorders and Therapeutic Nutrition (VV130)
      Diagnosis of Human Disease (VV720) (New March 2000)
    • Accession Number:
      7235-40-7; 9007-41-4; 59-30-3; 59-67-6; 68-26-8; 83-88-5
    • Publication Information:
      Thesis; ISBN:9789461738554
    • Accession Number:
      20143255873
    • Copyright:
      ©2014 CAB International
  • Citations
    • ABNT:
      TALSMA, E. F. Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren. 2014. Wageningen Universiteit (Wageningen University), Wageningen; Netherlands, 2014. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20143255873. Acesso em: 27 set. 2020.
    • AMA:
      Talsma EF. Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren. Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren. 2014:143. Accessed September 27, 2020. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20143255873
    • APA:
      Talsma, E. F. (2014). Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren [Wageningen Universiteit (Wageningen University)]. In Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren (p. 143).
    • Chicago/Turabian: Author-Date:
      Talsma, E. F. 2014. “Yellow Cassava: Efficacy of Provitamin A Rich Cassava on Improvement of Vitamin A Status in Kenyan Schoolchildren.” Yellow Cassava: Efficacy of Provitamin A Rich Cassava on Improvement of Vitamin A Status in Kenyan Schoolchildren. Wageningen; Netherlands: Wageningen Universiteit (Wageningen University). http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20143255873.
    • Harvard:
      Talsma, E. F. (2014) Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren, Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren. Wageningen Universiteit (Wageningen University). Available at: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20143255873 (Accessed: 27 September 2020).
    • Harvard: Australian:
      Talsma, EF 2014, ‘Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren’, Wageningen Universiteit (Wageningen University), Wageningen; Netherlands, Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren, p. 143, viewed 27 September 2020, .
    • MLA:
      Talsma, E. F. “Yellow Cassava: Efficacy of Provitamin A Rich Cassava on Improvement of Vitamin A Status in Kenyan Schoolchildren.” Yellow Cassava: Efficacy of Provitamin A Rich Cassava on Improvement of Vitamin A Status in Kenyan Schoolchildren, Wageningen Universiteit (Wageningen University), 2014, p. 143. EBSCOhost, search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20143255873.
    • Chicago/Turabian: Humanities:
      Talsma, E. F. “Yellow Cassava: Efficacy of Provitamin A Rich Cassava on Improvement of Vitamin A Status in Kenyan Schoolchildren.” Yellow Cassava: Efficacy of Provitamin A Rich Cassava on Improvement of Vitamin A Status in Kenyan Schoolchildren. Wageningen Universiteit (Wageningen University), 2014. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20143255873.
    • Vancouver/ICMJE:
      Talsma EF. Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren [Internet]. Yellow cassava: efficacy of provitamin A rich cassava on improvement of vitamin A status in Kenyan schoolchildren. [Wageningen; Netherlands]: Wageningen Universiteit (Wageningen University); 2014 [cited 2020 Sep 27]. p. 143. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20143255873