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Encapsulation of lipids to delay lipolysis and reduce food intake: 'from encapsulate design towards human application'.

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  • Additional Information
    • Author(s):
    • Address:
      2 College Cobbenhagen, Brittendreef 5, 5012 AE Tilburg, Netherlands.; [email protected]
    • Publication Information:
      Netherlands
    • Abstract:
      In an ideal scenario, the increasing prevalence of overweight and obesity is counteracted by an effective preferably non-invasive weight management strategy. In this thesis, we targeted on physiological feedback involved in hunger regulation, via the so-called "ileal brake" mechanism. The ileal brake is activated when non-absorbed lipid metabolites are sensed in the ileum, and induce satiety. Ileal brake activation has been proven effective through direct delivery (via intubation) of lipids into the ileum. However, to be part of a non-invasive weight management strategy, the lipid should be ingested through the normal route of food intake, where it will face the efficient digestive processes of the human gastrointestinal (GI) tract, forming lipid metabolites that will be absorbed before reaching the ileum. When lipid digestion is delayed, i.e., taking place further down the small intestine, the formed metabolites can be sensed in the ileum and, the ileal brake mechanism can be activated.
    • Subject Terms:
      Human Nutrition
    • Subject Terms:
    • Accession Number:
      fat metabolism, fatness, lipins
    • CABICODES:
      Food Processing (General) (QQ100)
      Physiology of Human Nutrition (VV120)
      Nutrition Related Disorders and Therapeutic Nutrition (VV130)
    • Publication Information:
      Thesis; ISBN:9789463432382URL:http://edepot.wur.nl/429534
    • Accession Number:
      20183209325
    • Copyright:
      ©2018 CAB International
  • Citations
    • ABNT:
      CORSTENS, M. N. Encapsulation of lipids to delay lipolysis and reduce food intake: “from encapsulate design towards human application”. 2018. Wageningen University, Wageningen; Netherlands, 2018. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20183209325. Acesso em: 27 set. 2020.
    • AMA:
      Corstens MN. Encapsulation of lipids to delay lipolysis and reduce food intake: “from encapsulate design towards human application.” Encapsulation of lipids to delay lipolysis and reduce food intake: “From encapsulate design towards human application.” 2018:200. Accessed September 27, 2020. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20183209325
    • APA:
      Corstens, M. N. (2018). Encapsulation of lipids to delay lipolysis and reduce food intake: “from encapsulate design towards human application” [Wageningen University]. In Encapsulation of lipids to delay lipolysis and reduce food intake: “From encapsulate design towards human application” (p. 200).
    • Chicago/Turabian: Author-Date:
      Corstens, M. N. 2018. “Encapsulation of Lipids to Delay Lipolysis and Reduce Food Intake: ‘From Encapsulate Design towards Human Application.’” Encapsulation of Lipids to Delay Lipolysis and Reduce Food Intake: “From Encapsulate Design towards Human Application.” Wageningen; Netherlands: Wageningen University. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20183209325.
    • Harvard:
      Corstens, M. N. (2018) Encapsulation of lipids to delay lipolysis and reduce food intake: ‘from encapsulate design towards human application’, Encapsulation of lipids to delay lipolysis and reduce food intake: ‘From encapsulate design towards human application’. Wageningen University. Available at: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20183209325 (Accessed: 27 September 2020).
    • Harvard: Australian:
      Corstens, MN 2018, ‘Encapsulation of lipids to delay lipolysis and reduce food intake: “from encapsulate design towards human application”’, Wageningen University, Wageningen; Netherlands, Encapsulation of lipids to delay lipolysis and reduce food intake: ‘From encapsulate design towards human application’, p. 200, viewed 27 September 2020, .
    • MLA:
      Corstens, M. N. “Encapsulation of Lipids to Delay Lipolysis and Reduce Food Intake: ‘From Encapsulate Design towards Human Application.’” Encapsulation of Lipids to Delay Lipolysis and Reduce Food Intake: “From Encapsulate Design towards Human Application,” Wageningen University, 2018, p. 200. EBSCOhost, search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20183209325.
    • Chicago/Turabian: Humanities:
      Corstens, M. N. “Encapsulation of Lipids to Delay Lipolysis and Reduce Food Intake: ‘From Encapsulate Design towards Human Application.’” Encapsulation of Lipids to Delay Lipolysis and Reduce Food Intake: “From Encapsulate Design towards Human Application.” Wageningen University, 2018. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20183209325.
    • Vancouver/ICMJE:
      Corstens MN. Encapsulation of lipids to delay lipolysis and reduce food intake: “from encapsulate design towards human application” [Internet]. Encapsulation of lipids to delay lipolysis and reduce food intake: “From encapsulate design towards human application.” [Wageningen; Netherlands]: Wageningen University; 2018 [cited 2020 Sep 27]. p. 200. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20183209325