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Bloodstream infections with ESBL-producing Enterobacterales : prediction, rapid diagnosis and molecular epidemiology.

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  • Additional Information
    • Author(s):
    • Address:
      Department Of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
    • Publication Information:
      Sweden
    • Abstract:
      The objective of the article was to aimed to improve care for patients with EPE BSI in three ways: early prediction, rapid diagnosis and increased understanding of resistance transmission and the importance of microbial virulence for the severity of disease. In conclusion, the treatment of patients with EPE BSI could be improved by these results. Use of the Stockholm score identified many, but not all, patients at risk of EPE BSI, thereby improving the appropriateness of empirical therapy. Rapid disk diffusion with adapted breakpoints gave accurate results and would enable early correction of therapy. blaNDM-1 was found in diverse sequence types of K. pneumoniae. The virulence gene is was associated with septic shock in EPE BSI and might have potential as an anti-virulence treatment target.
    • Number of References:
      208 ref.
    • Subject Terms:
      Public Health
    • Subject Terms:
    • Accession Number:
      chemotherapy, bacterial infections, bacterioses, bacterium
    • CABICODES:
      Prion, Viral, Bacterial and Fungal Pathogens of Humans (VV210) (New March 2000)
      Diagnosis of Human Disease (VV720) (New March 2000)
      Genetics and Molecular Biology of Microorganisms (ZZ395) (New March 2000)
      General Molecular Biology (ZZ360) (Discontinued March 2000)
    • Publication Information:
      Thesis; URL:https://openarchive.ki.se/xmlui/handle/10616/46888
    • Accession Number:
      20203185620
    • Copyright:
      ©2019 CAB International
  • Citations
    • ABNT:
      FRÖDING, I. Bloodstream infections with ESBL-producing Enterobacterales : prediction, rapid diagnosis and molecular epidemiology. 2019. Karolinska Institutet, Stockholm; Sweden, 2019. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20203185620. Acesso em: 4 ago. 2020.
    • AMA:
      Fröding I. Bloodstream infections with ESBL-producing Enterobacterales : prediction, rapid diagnosis and molecular epidemiology. Bloodstream infections with ESBL-producing Enterobacterales: prediction, rapid diagnosis and molecular epidemiology. 2019:94. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20203185620. Accessed August 4, 2020.
    • AMA11:
      Fröding I. Bloodstream infections with ESBL-producing Enterobacterales : prediction, rapid diagnosis and molecular epidemiology. Bloodstream infections with ESBL-producing Enterobacterales: prediction, rapid diagnosis and molecular epidemiology. 2019:94. Accessed August 4, 2020. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20203185620
    • APA:
      Fröding, I. (2019). Bloodstream infections with ESBL-producing Enterobacterales : prediction, rapid diagnosis and molecular epidemiology [Karolinska Institutet]. In Bloodstream infections with ESBL-producing Enterobacterales: prediction, rapid diagnosis and molecular epidemiology (p. 94).
    • Chicago/Turabian: Author-Date:
      Fröding, I. 2019. “Bloodstream Infections with ESBL-Producing Enterobacterales : Prediction, Rapid Diagnosis and Molecular Epidemiology.” Bloodstream Infections with ESBL-Producing Enterobacterales: Prediction, Rapid Diagnosis and Molecular Epidemiology. Stockholm; Sweden: Karolinska Institutet. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20203185620.
    • Harvard:
      Fröding, I. (2019) Bloodstream infections with ESBL-producing Enterobacterales : prediction, rapid diagnosis and molecular epidemiology, Bloodstream infections with ESBL-producing Enterobacterales: prediction, rapid diagnosis and molecular epidemiology. Karolinska Institutet. Available at: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20203185620 (Accessed: 4 August 2020).
    • Harvard: Australian:
      Fröding, I 2019, ‘Bloodstream infections with ESBL-producing Enterobacterales : prediction, rapid diagnosis and molecular epidemiology’, Karolinska Institutet, Stockholm; Sweden, Bloodstream infections with ESBL-producing Enterobacterales: prediction, rapid diagnosis and molecular epidemiology, p. 94, viewed 4 August 2020, .
    • MLA:
      Fröding, I. “Bloodstream Infections with ESBL-Producing Enterobacterales : Prediction, Rapid Diagnosis and Molecular Epidemiology.” Bloodstream Infections with ESBL-Producing Enterobacterales: Prediction, Rapid Diagnosis and Molecular Epidemiology, Karolinska Institutet, 2019, p. 94. EBSCOhost, search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20203185620.
    • Chicago/Turabian: Humanities:
      Fröding, I. “Bloodstream Infections with ESBL-Producing Enterobacterales : Prediction, Rapid Diagnosis and Molecular Epidemiology.” Bloodstream Infections with ESBL-Producing Enterobacterales: Prediction, Rapid Diagnosis and Molecular Epidemiology. Karolinska Institutet, 2019. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20203185620.
    • Vancouver/ICMJE:
      Fröding I. Bloodstream infections with ESBL-producing Enterobacterales : prediction, rapid diagnosis and molecular epidemiology [Internet]. Bloodstream infections with ESBL-producing Enterobacterales: prediction, rapid diagnosis and molecular epidemiology. [Stockholm; Sweden]: Karolinska Institutet; 2019 [cited 2020 Aug 4]. p. 94. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lhh&AN=20203185620