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Genotype and severity of long QT syndrome.

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  • Author(s): Towbin JA;Towbin JA; Wang Z; Li H
  • Source:
    Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2001 Apr; Vol. 29 (4 Pt 2), pp. 574-9.
  • Publication Type:
    Congress
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model: Print Cited Medium: Print ISSN: 0090-9556 (Print) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab. Dispos. Subsets: MEDLINE
    • Publication Information:
      Original Publication: [Bethesda, Md., etc., American Society for Pharmacology and Experimental Therapeutics, etc.]
    • Subject Terms:
    • Abstract:
      Sudden cardiac death occurs in the United States with an incidence greater than 300,000 persons per year. The underlying cause of death is commonly considered to be due to primary or secondary arrhythmias. In cases in which no structural heart disease can be identified, the long QT syndromes (LQTS) are now commonly considered as likely causes. Multiple genes causing LQTS have been identified thus far, all encoding cardiac ion channels. These include two potassium channel alpha-subunits (KVLQT1, HERG), two potassium channel beta-subunits (minK, MiRP1), and one sodium channel gene (SCN5A). The purpose of this review is to describe the current understanding of the molecular genetics of LQTS and the resultant phenotypes.
    • Publication Date:
      Date Created: 20010322 Date Completed: 20010614 Latest Revision: 20181130
    • Publication Date:
      20200827
    • Accession Number:
      11259355
  • Citations
    • ABNT:
      TOWBIN, J. A.; WANG, Z.; LI, H. Genotype and severity of long QT syndrome. Drug metabolism and disposition: the biological fate of chemicals, [s. l.], v. 29, n. 4 Pt 2, p. 574–579, 2001. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdc&AN=11259355. Acesso em: 21 out. 2020.
    • AMA:
      Towbin JA, Wang Z, Li H. Genotype and severity of long QT syndrome. Drug metabolism and disposition: the biological fate of chemicals. 2001;29(4 Pt 2):574-579. Accessed October 21, 2020. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdc&AN=11259355
    • APA:
      Towbin, J. A., Wang, Z., & Li, H. (2001). Genotype and severity of long QT syndrome. Drug Metabolism and Disposition: The Biological Fate of Chemicals, 29(4 Pt 2), 574–579.
    • Chicago/Turabian: Author-Date:
      Towbin, J A, Z Wang, and H Li. 2001. “Genotype and Severity of Long QT Syndrome.” Drug Metabolism and Disposition: The Biological Fate of Chemicals 29 (4 Pt 2): 574–79. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdc&AN=11259355.
    • Harvard:
      Towbin, J. A., Wang, Z. and Li, H. (2001) ‘Genotype and severity of long QT syndrome’, Drug metabolism and disposition: the biological fate of chemicals, 29(4 Pt 2), pp. 574–579. Available at: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdc&AN=11259355 (Accessed: 21 October 2020).
    • Harvard: Australian:
      Towbin, JA, Wang, Z & Li, H 2001, ‘Genotype and severity of long QT syndrome’, Drug metabolism and disposition: the biological fate of chemicals, vol. 29, no. 4 Pt 2, pp. 574–579, viewed 21 October 2020, .
    • MLA:
      Towbin, J. A., et al. “Genotype and Severity of Long QT Syndrome.” Drug Metabolism and Disposition: The Biological Fate of Chemicals, vol. 29, no. 4 Pt 2, Apr. 2001, pp. 574–579. EBSCOhost, search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdc&AN=11259355.
    • Chicago/Turabian: Humanities:
      Towbin, J A, Z Wang, and H Li. “Genotype and Severity of Long QT Syndrome.” Drug Metabolism and Disposition: The Biological Fate of Chemicals 29, no. 4 Pt 2 (April 2001): 574–79. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdc&AN=11259355.
    • Vancouver/ICMJE:
      Towbin JA, Wang Z, Li H. Genotype and severity of long QT syndrome. Drug metabolism and disposition: the biological fate of chemicals [Internet]. 2001 Apr [cited 2020 Oct 21];29(4 Pt 2):574–9. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdc&AN=11259355