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Academic Journal

Anti-Ro52 antibody acts on the S5-pore linker of hERG to chronically reduce channel expression.

  • Authors : Szendrey J; Department of Biomedical and Molecular Sciences, Queen's University, 18 Stuart Street, Kingston, Canada.; Lamothe SM

Subjects: Antibodies, Antinuclear/Antibodies, Antinuclear/Antibodies, Antinuclear/*metabolism ; ERG1 Potassium Channel/ERG1 Potassium Channel/ERG1 Potassium Channel/*metabolism; Aged

  • Source: Cardiovascular research [Cardiovasc Res] 2019 Aug 01; Vol. 115 (10), pp. 1500-1511.Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245

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Academic Journal

LUF7244 plus Dofetilide Rescues Aberrant K v 11.1 Trafficking and Produces Functional I Kv11.1 .

  • Authors : Qile M; Department of Medical Physiology, University Medical Center Utrecht, Utrecht, The Netherlands (M.Q., Y.J., M.J.C.H., F.R., D.F., W.B.H., M.A.G.H.); Department of Physiology, University of Kentucky, Lexington, Kentucky (T.D.G., B.P.D.)

Subjects: Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/*pharmacology ; ERG1 Potassium Channel/ERG1 Potassium Channel/ERG1 Potassium Channel/*drug effects ; Organic Chemicals/Organic Chemicals/Organic Chemicals/*pharmacology

  • Source: Molecular pharmacology [Mol Pharmacol] 2020 Jun; Vol. 97 (6), pp. 355-364. Date of Electronic Publication: 2020 Apr 02.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model:

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Academic Journal

HERG channel and cancer: A mechanistic review of carcinogenic processes and therapeutic potential.

  • Authors : He S; Department of Surgery, Neuroscience Research Group, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.; Moutaoufik MT

Subjects: Carcinogenesis/Carcinogenesis/Carcinogenesis/*pathology ; ERG1 Potassium Channel/ERG1 Potassium Channel/ERG1 Potassium Channel/*metabolism ; Integrin beta1/Integrin beta1/Integrin beta1/*metabolism

  • Source: Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2020 Apr; Vol. 1873 (2), pp. 188355. Date of Electronic Publication: 2020 Mar 02.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9806362 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Selectivity filter modalities and rapid inactivation of the hERG1 channel.

  • Authors : Miranda WE; Centre for Molecular Simulation, Department of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.; DeMarco KR

Subjects: ERG1 Potassium Channel/ERG1 Potassium Channel/ERG1 Potassium Channel/*chemistry ; ERG1 Potassium Channel/ERG1 Potassium Channel/ERG1 Potassium Channel/*metabolism; Amino Acid Motifs

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Feb 11; Vol. 117 (6), pp. 2795-2804. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Interleukin-6 inhibition of hERG underlies risk for acquired long QT in cardiac and systemic inflammation.

  • Authors : Aromolaran AS; Cardiovascular Research Program, VA New York Harbor Healthcare System, Brooklyn, New York, United States of America.; Department of Cell Biology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York, United States of America.

Subjects: Arrhythmias, Cardiac/Arrhythmias, Cardiac/Arrhythmias, Cardiac/*metabolism ; ERG1 Potassium Channel/ERG1 Potassium Channel/ERG1 Potassium Channel/*metabolism ; Inflammation/Inflammation/Inflammation/*metabolism

  • Source: PloS one [PLoS One] 2018 Dec 06; Vol. 13 (12), pp. e0208321. Date of Electronic Publication: 2018 Dec 06 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Increased Smooth Muscle Kv11.1 Channel Expression in Pulmonary Hypertension and Protective Role of Kv11.1 Channel Blocker Dofetilide.

  • Authors : Shults NV; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, District of Columbia.; Rybka V

Subjects: Arrhythmias, Cardiac/Arrhythmias, Cardiac/Arrhythmias, Cardiac/*prevention & control ; ERG1 Potassium Channel/ERG1 Potassium Channel/ERG1 Potassium Channel/*antagonists & inhibitors ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*drug effects

  • Source: The American journal of pathology [Am J Pathol] 2020 Jan; Vol. 190 (1), pp. 48-56. Date of Electronic Publication: 2019 Dec 12.Publisher: Elsevier Country of Publication: United States NLM ID: 0370502 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Cardiac safety of second-generation H 1 -antihistamines when updosed in chronic spontaneous urticaria.

  • Authors : Cataldi M; Section of Pharmacology, Department of Neuroscience, School of Medicine, University of Naples Federico II, Naples, Italy.; Maurer M

Subjects: Cardiotoxicity*/Cardiotoxicity*/Cardiotoxicity*/immunology ; Cardiotoxicity*/Cardiotoxicity*/Cardiotoxicity*/pathology ; Cardiotoxicity*/Cardiotoxicity*/Cardiotoxicity*/prevention & control

  • Source: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2019 Dec; Vol. 49 (12), pp. 1615-1623. Date of Electronic Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8906443 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The influence of hERG1a and hERG1b isoforms on drug safety screening in iPSC-CMs.

  • Authors : Goversen B; Department of Medical Physiology, Division Heart & Lungs, University Medical Center Utrecht, the Netherlands.; Jonsson MK

Subjects: ERG1 Potassium Channel/ERG1 Potassium Channel/ERG1 Potassium Channel/*metabolism ; Induced Pluripotent Stem Cells/Induced Pluripotent Stem Cells/Induced Pluripotent Stem Cells/*metabolism ; Myocytes, Cardiac/Myocytes, Cardiac/Myocytes, Cardiac/*metabolism

  • Source: Progress in biophysics and molecular biology [Prog Biophys Mol Biol] 2019 Dec; Vol. 149, pp. 86-98. Date of Electronic Publication: 2019 Feb 27.Publisher: Pergamon Press Country of Publication: England NLM ID: 0401233 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

MicroRNA 362-3p Reduces hERG-related Current and Inhibits Breast Cancer Cells Proliferation.

  • Authors : Assiri AA; Department of Pharmacy Practice, College of Pharmacy, Purdue University, West Lafayette, IN, U.S.A.; Department of Clinical Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia.

Subjects: Cell Proliferation* ; Membrane Potentials*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism

  • Source: Cancer genomics & proteomics [Cancer Genomics Proteomics] 2019 Nov-Dec; Vol. 16 (6), pp. 433-442.Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 101188791 Publication Model: Print Cited Medium:

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Academic Journal

Gating mechanism of Kv11.1 (hERG) K + channels without covalent connection between voltage sensor and pore domains.

  • Authors : de la Peña P; Departamento de Bioquímica y Biología Molecular, Edificio Santiago Gascón, Campus de El Cristo, Universidad de Oviedo, 33006, Oviedo, Asturias, Spain. .; Domínguez P

Subjects: Ion Channel Gating*; ERG1 Potassium Channel/ERG1 Potassium Channel/ERG1 Potassium Channel/*metabolism; Amino Acid Substitution

  • Source: Pflugers Archiv : European journal of physiology [Pflugers Arch] 2018 Mar; Vol. 470 (3), pp. 517-536. Date of Electronic Publication: 2017 Dec 21.Publisher: Springer Country of Publication: Germany NLM ID: 0154720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2013

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  • 1-10 of  1,858 results for ""ERG1 Potassium Channel""