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Academic Journal

Thioridazine Induces Cardiotoxicity via Reactive Oxygen Species-Mediated hERG Channel Deficiency and L-Type Calcium Channel Activation.

  • Authors : Liu Y; Department of Pharmacology, College of Pharmacy, Harbin Medical University, Harbin, China.; Xu X

Subjects: Action Potentials/Action Potentials/Action Potentials/*drug effects ; Calcium Channels, L-Type/Calcium Channels, L-Type/Calcium Channels, L-Type/*metabolism ; Cardiotoxicity/Cardiotoxicity/Cardiotoxicity/*metabolism

  • Source: Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2020 Jan 22; Vol. 2020, pp. 3690123. Date of Electronic Publication: 2020 Jan 22 (Print Publication: 2020).Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 101479826 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Tetrandrine, a novel inhibitor of ether-à-go-go-1 (Eag1), targeted to cervical cancer development.

  • Authors : Wang X; State Key Laboratory of Reliability and Intelligence of Electrical Equipment, School of Electrical Engineering, Hebei University of Technology, Tianjin, China.; Key Laboratory of Molecular Biophysics, Hebei Province, School of Science, Hebei University of Technology, Tianjin, China.

Subjects: Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*pharmacology ; Benzylisoquinolines/Benzylisoquinolines/Benzylisoquinolines/*pharmacology ; Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/*antagonists & inhibitors

  • Source: Journal of cellular physiology [J Cell Physiol] 2019 May; Vol. 234 (5), pp. 7161-7173. Date of Electronic Publication: 2018 Oct 26.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effectiveness of nalbuphine, a κ-opioid receptor agonist and μ-opioid receptor antagonist, in the inhibition of I Na , I K(M) , and I K(erg) unlinked to interaction with opioid receptors.

  • Authors : Liu YY; Division of Trauma, Department of Emergency, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan.; Hsiao HT

Subjects: Analgesics, Opioid/Analgesics, Opioid/Analgesics, Opioid/*pharmacology ; Delayed Rectifier Potassium Channels/Delayed Rectifier Potassium Channels/Delayed Rectifier Potassium Channels/*antagonists & inhibitors ; Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/*antagonists & inhibitors

  • Source: Drug development research [Drug Dev Res] 2019 Sep; Vol. 80 (6), pp. 846-856. Date of Electronic Publication: 2019 Jul 13.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Identification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels.

  • Authors : Wang ZJ; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA.; Tiwari PB

Subjects: Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/*antagonists & inhibitors ; Potassium Channel Blockers/Potassium Channel Blockers/Potassium Channel Blockers/*pharmacology ; Undecylenic Acids/Undecylenic Acids/Undecylenic Acids/*pharmacology

  • Source: BMC pharmacology & toxicology [BMC Pharmacol Toxicol] 2019 Jul 17; Vol. 20 (1), pp. 42. Date of Electronic Publication: 2019 Jul 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101590449 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-6511

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Academic Journal

Computational determination of hERG-related cardiotoxicity of drug candidates.

  • Authors : Lee HM; School of integrative engineering, Chung-Ang University, Seoul, Republic of Korea.; Yu MS

Subjects: Neural Networks, Computer*; Cardiotoxicity/Cardiotoxicity/Cardiotoxicity/*metabolism ; Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/*metabolism

  • Source: BMC bioinformatics [BMC Bioinformatics] 2019 May 29; Vol. 20 (Suppl 10), pp. 250. Date of Electronic Publication: 2019 May 29.Publisher: BioMed Central Country of Publication: England NLM ID: 100965194 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2105

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Academic Journal

Functional analysis of KCNH2 gene mutations of type 2 long QT syndrome in larval zebrafish using microscopy and electrocardiography.

  • Authors : Tanaka Y; Department of Cardiovascular and Internal Medicine, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.; Hayashi K

Subjects: Mutation*; DNA/DNA/DNA/*genetics ; Electrocardiography/Electrocardiography/Electrocardiography/*methods Long Qt Syndrome 2

  • Source: Heart and vessels [Heart Vessels] 2019 Jan; Vol. 34 (1), pp. 159-166. Date of Electronic Publication: 2018 Jul 25.Publisher: Springer Verlag Country of Publication: Japan NLM ID: 8511258 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Identification of small-molecule ion channel modulators in C. elegans channelopathy models.

  • Authors : Jiang Q; Institute of Neuroscience and State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.; University of Chinese Academy of Sciences, 100049, Beijing, China.

Subjects: Channelopathies/Channelopathies/Channelopathies/*genetics ; Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/*genetics; Animals

  • Source: Nature communications [Nat Commun] 2018 Sep 26; Vol. 9 (1), pp. 3941. Date of Electronic Publication: 2018 Sep 26.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

ERG Channels Regulate Excitability in Stellate and Bushy Cells of Mice Ventral Cochlear Nucleus.

  • Authors : Yildirim C; Department of Physiology, Faculty of Medicine, Kafkas University, 36100, Kars, Turkey. .; Bal R

Subjects: Cochlear Nucleus/Cochlear Nucleus/Cochlear Nucleus/*metabolism ; Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/*metabolism; Action Potentials/Action Potentials/Action Potentials/drug effects

  • Source: The Journal of membrane biology [J Membr Biol] 2018 Dec; Vol. 251 (5-6), pp. 711-722. Date of Electronic Publication: 2018 Sep 11.Publisher: Springer Country of Publication: United States NLM ID: 0211301 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Increased Expression of Kv10.2 in the Hippocampus Attenuates Valproic Acid-Induced Autism-Like Behaviors in Rats.

  • Authors : Wang J; School of Life Sciences, Shanghai University, Shanghai, 200444, China.; Feng S

Subjects: Autistic Disorder/Autistic Disorder/Autistic Disorder/*therapy ; Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/*metabolism ; Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/*therapeutic use

  • Source: Neurochemical research [Neurochem Res] 2019 Dec; Vol. 44 (12), pp. 2796-2808. Date of Electronic Publication: 2019 Nov 15.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Inhibition of human ether à go-go potassium channels by Ca2+/calmodulin binding to the cytosolic N- and C-termini.

  • Authors : Ziechner U; Institute of Molecular Cell Biology, Research Unit Molecular and Cellular Biophysics, Friedrich Schiller University Jena, Germany.; Schönherr R

Subjects: Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/*antagonists & inhibitors ; Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/Ether-A-Go-Go Potassium Channels/*chemistry; Amino Acid Sequence

  • Source: The FEBS journal [FEBS J] 2006 Mar; Vol. 273 (5), pp. 1074-86.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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  • 1-10 of  3,228 results for ""Ether-A-Go-Go Potassium Channels""