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Academic Journal

The auxiliary subunit KCNE1 regulates KCNQ1 channel response to sustained calcium-dependent PKC activation.

  • Authors : Xu Parks X; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States of America.; Qudsi H

Subjects: Calcium/Calcium/Calcium/*metabolism ; KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/*metabolism ; Myocytes, Cardiac/Myocytes, Cardiac/Myocytes, Cardiac/*metabolism

  • Source: PloS one [PLoS One] 2020 Aug 24; Vol. 15 (8), pp. e0237591. Date of Electronic Publication: 2020 Aug 24 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Upgraded molecular models of the human KCNQ1 potassium channel.

  • Authors : Kuenze G; Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America.; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America.

Subjects: Models, Molecular*; KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/*chemistry; Humans

  • Source: PloS one [PLoS One] 2019 Sep 13; Vol. 14 (9), pp. e0220415. Date of Electronic Publication: 2019 Sep 13 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A conserved arginine/lysine-based motif promotes ER export of KCNE1 and KCNE2 to regulate KCNQ1 channel activity.

  • Authors : Hu B; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Zeng WP

Subjects: Endoplasmic Reticulum/Endoplasmic Reticulum/Endoplasmic Reticulum/*metabolism ; KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/*metabolism ; Potassium Channels, Voltage-Gated/Potassium Channels, Voltage-Gated/Potassium Channels, Voltage-Gated/*chemistry

  • Source: Channels (Austin, Tex.) [Channels (Austin)] 2019 Dec; Vol. 13 (1), pp. 483-497.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101321614 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Effects of protein-protein interactions and ligand binding on the ion permeation in KCNQ1 potassium channel.

  • Authors : Jalily Hasani H; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada.; Ganesan A

Subjects: KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/*metabolism; Humans ; Ligands

  • Source: PloS one [PLoS One] 2018 Feb 14; Vol. 13 (2), pp. e0191905. Date of Electronic Publication: 2018 Feb 14 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

KCNQ1 rescues TMC1 plasma membrane expression but not mechanosensitive channel activity.

  • Authors : Harkcom WT; Pharmacology Department, Weill Medical College of Cornell University, New York, New York.; Papanikolaou M

Subjects: KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/*metabolism ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism; Amino Acid Motifs

  • Source: Journal of cellular physiology [J Cell Physiol] 2019 Aug; Vol. 234 (8), pp. 13361-13369. Date of Electronic Publication: 2019 Jan 05.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Repurposing Approved Drugs as Inhibitors of K v 7.1 and Na v 1.8 to Treat Pitt Hopkins Syndrome.

  • Authors : Ekins S; Collaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina, 27606, USA. .; Gerlach J

Subjects: Dihydropyridines/Dihydropyridines/Dihydropyridines/*pharmacology ; Drug Repositioning/Drug Repositioning/Drug Repositioning/*methods ; Hyperventilation/Hyperventilation/Hyperventilation/*drug therapy Pitt-Hopkins syndrome

  • Source: Pharmaceutical research [Pharm Res] 2019 Jul 22; Vol. 36 (9), pp. 137. Date of Electronic Publication: 2019 Jul 22.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

ω-6 and ω-9 polyunsaturated fatty acids with double bonds near the carboxyl head have the highest affinity and largest effects on the cardiac I K s potassium channel.

  • Authors : Bohannon BM; Department of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, Florida.; Perez ME

Subjects: Fatty Acids, Omega-6/Fatty Acids, Omega-6/Fatty Acids, Omega-6/*pharmacology ; Fatty Acids, Unsaturated/Fatty Acids, Unsaturated/Fatty Acids, Unsaturated/*pharmacology ; KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/*agonists

  • Source: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2019 Feb; Vol. 225 (2), pp. e13186. Date of Electronic Publication: 2018 Oct 17.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262545 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A novel mutation KCNQ1p.Thr312del is responsible for long QT syndrome type 1.

  • Authors : Chen XM; Department of Cardiology, School of Medicine, Xinhua Hospital, Shanghai Jiao Tong University, 1665 Kongjiang Road, Shanghai, 200092, China.; Guo K

Subjects: Mutation*; DNA/DNA/DNA/*genetics ; KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/KCNQ1 Potassium Channel/*genetics

  • Source: Heart and vessels [Heart Vessels] 2019 Jan; Vol. 34 (1), pp. 177-188. Date of Electronic Publication: 2018 Jul 14.Publisher: Springer Verlag Country of Publication: Japan NLM ID: 8511258 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Report

Decoding KCNH2 variants of unknown significance.

  • Authors : Vanoye CG; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.; George AL Jr

Subjects: KCNQ1 Potassium Channel* ; Potassium Channels*; ERG1 Potassium Channel

  • Source: Heart rhythm [Heart Rhythm] 2020 Mar; Vol. 17 (3), pp. 501-502. Date of Electronic Publication: 2019 Oct 05.Publisher: Elsevier Country of Publication: United States NLM ID: 101200317 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  2,253 results for ""KCNQ1 Potassium Channel""