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Academic Journal

SCN5A mutation G615E results in Na V 1.5 voltage-gated sodium channels with normal voltage-dependent function yet loss of mechanosensitivity.

  • Authors : Strege PR; a Enteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic , Rochester , MN , USA.; Mercado-Perez A

Subjects: Mutation, Missense*; NAV1.5 Voltage-Gated Sodium Channel/NAV1.5 Voltage-Gated Sodium Channel/NAV1.5 Voltage-Gated Sodium Channel/*genetics ; NAV1.5 Voltage-Gated Sodium Channel/NAV1.5 Voltage-Gated Sodium Channel/NAV1.5 Voltage-Gated Sodium Channel/*metabolism

  • Source: Channels (Austin, Tex.) [Channels (Austin)] 2019 Dec; Vol. 13 (1), pp. 287-298.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101321614 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo.

  • Authors : Man JCK; Department of Medical Biology, Amsterdam Cardiovascular Sciences, Academic Medical Center, Amsterdam, The Netherlands.; Mohan RA

Subjects: Heart/Heart/Heart/*embryology ; Heart Conduction System/Heart Conduction System/Heart Conduction System/*metabolism ; Myocardium/Myocardium/Myocardium/*metabolism

  • Source: Nature communications [Nat Commun] 2019 Oct 30; Vol. 10 (1), pp. 4943. Date of Electronic Publication: 2019 Oct 30.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Clinical characterisation of a novel SCN5A variant associated with progressive malignant arrhythmia and dilated cardiomyopathy.

  • Authors : Kean AC; Department of Pediatrics, Division of Pediatric Cardiology, Pediatric Electrophysiology, Indiana University School of Medicine, Indianapolis, IN, USA.; Helm BM

Subjects: Mutation*; Arrhythmias, Cardiac/Arrhythmias, Cardiac/Arrhythmias, Cardiac/*genetics ; Cardiomyopathy, Dilated/Cardiomyopathy, Dilated/Cardiomyopathy, Dilated/*genetics

  • Source: Cardiology in the young [Cardiol Young] 2019 Oct; Vol. 29 (10), pp. 1257-1263.Publisher: Cambridge University Press Country of Publication: England NLM ID: 9200019 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Voltage-gated sodium channel Nav1.5 promotes proliferation, migration and invasion of oral squamous cell carcinoma.

  • Authors : Zhang J; College & Hospital of Stomatology, Anhui Medical University, Key Lab of Oral Diseases Research of Anhui Province, Hefei, China.; Department of Immunology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.

Subjects: Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/*genetics ; Cell Movement/Cell Movement/Cell Movement/*genetics ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*genetics

  • Source: Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2019 Jun 20; Vol. 51 (6), pp. 562-570.Publisher: Oxford University Press Country of Publication: China NLM ID: 101206716 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy.

  • Authors : Salvarani N; Institute of Genetic and Biomedical Research (IRGB), UOS of Milan, National Research Council of Italy, Milan, 20138, Italy.; Department of Cardiovascular Medicine and Laboratory of Medical Biotechnology, Humanitas Clinical and Research Center - IRCCS, Rozzano (MI), 20089, Italy.

Subjects: Cardiomyopathy, Dilated/Cardiomyopathy, Dilated/Cardiomyopathy, Dilated/*genetics ; Heart Conduction System/Heart Conduction System/Heart Conduction System/*pathology ; Lamin Type A/Lamin Type A/Lamin Type A/*genetics

  • Source: Nature communications [Nat Commun] 2019 May 22; Vol. 10 (1), pp. 2267. Date of Electronic Publication: 2019 May 22.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ca 2+ -dependent regulation of sodium channels Na V 1.4 and Na V 1.5 is controlled by the post-IQ motif.

  • Authors : Yoder JB; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Ben-Johny M

Subjects: Calcium/Calcium/Calcium/*metabolism ; Calmodulin/Calmodulin/Calmodulin/*metabolism ; NAV1.4 Voltage-Gated Sodium Channel/NAV1.4 Voltage-Gated Sodium Channel/NAV1.4 Voltage-Gated Sodium Channel/*metabolism

  • Source: Nature communications [Nat Commun] 2019 Apr 03; Vol. 10 (1), pp. 1514. Date of Electronic Publication: 2019 Apr 03.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Change in late sodium current of atrial myocytes in spontaneously hypertensive rats with allocryptopine treatment.

  • Authors : Dong Y; Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China.; Huang Y

Subjects: Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/*pharmacology ; Atrial Fibrillation/Atrial Fibrillation/Atrial Fibrillation/*prevention & control ; Berberine Alkaloids/Berberine Alkaloids/Berberine Alkaloids/*pharmacology

  • Source: Cardiovascular journal of Africa [Cardiovasc J Afr] 2019 Mar/Apr 23; Vol. 30 (2), pp. 79-86. Date of Electronic Publication: 2019 Mar 14.Publisher: Clinics Cardive Pub Country of Publication: South Africa NLM ID: 101313864 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The citrus flavanone hesperetin preferentially inhibits slow-inactivating currents of a long QT syndrome type 3 syndrome Na + channel mutation.

  • Authors : Alvarez-Collazo J; Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.; López-Requena A

Subjects: Cardiac Conduction System Disease/Cardiac Conduction System Disease/Cardiac Conduction System Disease/*physiopathology ; Cardiotonic Agents/Cardiotonic Agents/Cardiotonic Agents/*pharmacology ; Heart/Heart/Heart/*drug effects Long QT syndrome type 3

  • Source: British journal of pharmacology [Br J Pharmacol] 2019 Apr; Vol. 176 (8), pp. 1090-1105. Date of Electronic Publication: 2019 Mar 27.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Brugada Syndrome Caused by Sodium Channel Dysfunction Associated with a SCN1B Variant A197V.

  • Authors : Wang L; Department of Cardiology, Nanjing Brain Hospital, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, People's Republic of China.; Han Z

Subjects: Brugada Syndrome/Brugada Syndrome/Brugada Syndrome/*genetics ; Brugada Syndrome/Brugada Syndrome/Brugada Syndrome/*physiopathology ; NAV1.5 Voltage-Gated Sodium Channel/NAV1.5 Voltage-Gated Sodium Channel/NAV1.5 Voltage-Gated Sodium Channel/*genetics

  • Source: Archives of medical research [Arch Med Res] 2020 Apr; Vol. 51 (3), pp. 245-253. Date of Electronic Publication: 2020 Mar 16.Publisher: Elsevier Science Country of Publication: United States NLM ID: 9312706 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lack of modulatory effect of the SCN5A R1193Q polymorphism on cardiac fast Na+ current at body temperature.

  • Authors : Abe M; Laboratory for Biological Information Processing, Graduate School of Science and Engineering, University of Toyama, Toyama City, Toyama, Japan.; Kinoshita K

Subjects: Body Temperature* ; Membrane Potentials* ; Mutation, Missense*

  • Source: PloS one [PLoS One] 2018 Nov 12; Vol. 13 (11), pp. e0207437. Date of Electronic Publication: 2018 Nov 12 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 of  1,680 results for ""NAV1.5 Voltage-Gated Sodium Channel""