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Academic Journal

MiR-18a-5p contributes to enhanced proliferation and migration of PASMCs via targeting Notch2 in pulmonary arterial hypertension.

  • Authors : Miao R; Department of Vascular Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China. Electronic address: .; Liu W

Subjects: MicroRNAs/MicroRNAs/MicroRNAs/*genetics ; Pulmonary Arterial Hypertension/Pulmonary Arterial Hypertension/Pulmonary Arterial Hypertension/*genetics ; Receptor, Notch2/Receptor, Notch2/Receptor, Notch2/*metabolism

  • Source: Life sciences [Life Sci] 2020 Sep 15; Vol. 257, pp. 117919. Date of Electronic Publication: 2020 Jun 22.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A phase 1 dose escalation and expansion study of Tarextumab (OMP-59R5) in patients with solid tumors.

  • Authors : Smith DC; University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA. .; University of Michigan Health System, 7302 Cancer Center, SPC 5946, 1500 East Medical Center Drive, Ann Arbor, MI, 48109, USA. .

Subjects: Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*administration & dosage ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*administration & dosage ; Neoplasms/Neoplasms/Neoplasms/*drug therapy

  • Source: Investigational new drugs [Invest New Drugs] 2019 Aug; Vol. 37 (4), pp. 722-730. Date of Electronic Publication: 2018 Dec 28.Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

MiR-431 is a prognostic marker and suppresses cell growth, migration and invasion by targeting NOTCH2 in melanoma.

  • Authors : Sun YW; Department of Oncology, Intravenous Drug Control Room; People's Hospital of Rizhao, Rizhao, Shandong, China. .

Subjects: Cell Proliferation*; Melanoma/Melanoma/Melanoma/*pathology ; MicroRNAs/MicroRNAs/MicroRNAs/*metabolism

  • Source: European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2019 May; Vol. 23 (9), pp. 3876-3884.Publisher: Verduci Country of Publication: Italy NLM ID: 9717360 Publication Model: Print Cited Medium: Internet ISSN: 2284-0729 (Electronic)

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Academic Journal

miR-195-5p/NOTCH2-mediated EMT modulates IL-4 secretion in colorectal cancer to affect M2-like TAM polarization.

  • Authors : Lin X; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, No.169 Donghu Road, Wuchang District, Wuhan, 430071, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, No.169 Donghu Road, Wuchang District, Wuhan, 430071, China.

Subjects: Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*metabolism ; Interleukin-4/Interleukin-4/Interleukin-4/*metabolism ; Macrophages/Macrophages/Macrophages/*metabolism

  • Source: Journal of hematology & oncology [J Hematol Oncol] 2019 Feb 26; Vol. 12 (1), pp. 20. Date of Electronic Publication: 2019 Feb 26.Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722

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Academic Journal

Notch - a possible mediator between Epstein-Barr virus infection and bone resorption in apical periodontitis.

  • Authors : Jakovljevic A; Department of Pathophysiology, School of Dental Medicine, University of Belgrade, Belgrade, Serbia.; Nikolic N

Subjects: Bone Resorption*/Bone Resorption*/Bone Resorption*/virology ; Epstein-Barr Virus Infections* ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/metabolism

  • Source: Acta odontologica Scandinavica [Acta Odontol Scand] 2020 Mar; Vol. 78 (2), pp. 126-131. Date of Electronic Publication: 2019 Sep 30.Publisher: Taylor & Francis Country of Publication: England NLM ID: 0370344 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Functional evidence implicating NOTCH2 missense mutations in primary ovarian insufficiency etiology.

  • Authors : Patiño LC; Center For Research in Genetics and Genomics (CIGGUR), GENIUROS Research Group, School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, Colombia.; Beau I

Subjects: Genetic Predisposition to Disease*; Mutation, Missense/Mutation, Missense/Mutation, Missense/*genetics ; Primary Ovarian Insufficiency/Primary Ovarian Insufficiency/Primary Ovarian Insufficiency/*genetics

  • Source: Human mutation [Hum Mutat] 2019 Jan; Vol. 40 (1), pp. 25-30. Date of Electronic Publication: 2018 Oct 22.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

miR-181b/Notch2 overcome chemoresistance by regulating cancer stem cell-like properties in NSCLC.

  • Authors : Wang X; The Department of Internal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China.; Meng Q

Subjects: Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*genetics ; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*pathology ; Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*genetics

  • Source: Stem cell research & therapy [Stem Cell Res Ther] 2018 Nov 23; Vol. 9 (1), pp. 327. Date of Electronic Publication: 2018 Nov 23.Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512

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Academic Journal

Notch2 signal is required for the maintenance of canine hemangiosarcoma cancer stem cell-like cells.

  • Authors : Aoshima K; Laboratory of Comparative Pathology, Department of Clinical Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo, Hokkaido, 060-0818, Japan. .; Fukui Y

Subjects: Hemangiosarcoma/Hemangiosarcoma/Hemangiosarcoma/*drug therapy ; Neoplastic Stem Cells/Neoplastic Stem Cells/Neoplastic Stem Cells/*drug effects ; Receptor, Notch2/Receptor, Notch2/Receptor, Notch2/*antagonists & inhibitors

  • Source: BMC veterinary research [BMC Vet Res] 2018 Oct 03; Vol. 14 (1), pp. 301. Date of Electronic Publication: 2018 Oct 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101249759 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-6148

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Academic Journal

Inflammation-induced colon cancer in uPA-deficient mice is associated with a deregulated expression of Notch signaling pathway components.

  • Authors : Afaloniati H; Laboratory of Biochemistry and Toxicology, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.; Karagiannis GS

Subjects: Gene Expression Regulation, Neoplastic* ; Signal Transduction*; Colonic Neoplasms/Colonic Neoplasms/Colonic Neoplasms/*metabolism

  • Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2020 Jan; Vol. 464 (1-2), pp. 181-191. Date of Electronic Publication: 2019 Nov 22.Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Alagille syndrome mutation update: Comprehensive overview of JAG1 and NOTCH2 mutation frequencies and insight into missense variant classification.

  • Authors : Gilbert MA; Division of Genomic Diagnostics, Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia and The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Bauer RC

Subjects: Loss of Function Mutation* ; Mutation, Missense*; Alagille Syndrome/Alagille Syndrome/Alagille Syndrome/*genetics

  • Source: Human mutation [Hum Mutat] 2019 Dec; Vol. 40 (12), pp. 2197-2220. Date of Electronic Publication: 2019 Aug 26.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  953 results for ""Receptor, Notch2""